Western blot analysis of extracts from cos-7 cells (Lane 2) and 3T3 cells (Lane 3), using MAP2K7 (Phospho-Thr275) Antibody. The lane on the left is treated with antigen-specific peptide.
Phospho-MAP2K7 (Thr275) Antibody
CSB-PA583333
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetMAP2K7
Overview
- SupplierCusabio
- Product NamePhospho-MAP2K7 (Thr275) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5609
- Target nameMAP2K7
- Target descriptionmitogen-activated protein kinase kinase 7
- Target synonymsc-Jun N-terminal kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 7; JNK-activating kinase 2; JNKK2; MAP kinase kinase 7; MAPK/ERK kinase 7; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPK kinase 4; SAPKK4; SAPKK-4; stress-activated protein kinase kinase 4
- HostRabbit
- IsotypeIgG
- Protein IDO14733
- Protein NameDual specificity mitogen-activated protein kinase kinase 7
- Scientific DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. Wu Z.,Mol. Cell. Biol. 17:7407-7416(1997). Lu X.,J. Biol. Chem. 272:24751-24754(1997). The MGC Project Team;Genome Res. 14:2121-2127(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203