
Western blot analysis of extracts from HT29 cells untreated or treated with PMA using Paxillin(Phospho-Tyr31) Antibody.
Phospho-PXN (Tyr31) Antibody
CSB-PA047961
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetPXN
Overview
- SupplierCusabio
- Product NamePhospho-PXN (Tyr31) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5829
- Target namePXN
- Target descriptionpaxillin
- Target synonymspaxillin; testicular tissue protein Li 134
- HostRabbit
- IsotypeIgG
- Protein IDP49023
- Protein NamePaxillin
- Scientific DescriptionAn antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) (paxillus means small stake or peg in Latin) as a protein tethered to the membrane at focal adhesions Davidson D, et al. (2001) EMBO J 20(13): 3414-3426. Fleming I, et al. (1999) Proc Natl Acad Sci U S A 96(3): 1123-1128. Goldberg MB. (2001) Microbiol Mol Biol Rev 65(4): 595-626. Kook S, et al. (2000) Mol Biol Cell 11(3): 929-939.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203