PI3 kinase p85 alpha antibody [N2C1], Internal
GTX111068
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPIK3R1
Overview
- SupplierGeneTex
- Product NamePI3 kinase p85 alpha antibody [N2C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.46 mg/ml
- ConjugateUnconjugated
- Gene ID5295
- Target namePIK3R1
- Target descriptionphosphoinositide-3-kinase regulatory subunit 1
- Target synonymsAGM7, GRB1, IMD36, p85, p85-ALPHA, p85alpha, phosphatidylinositol 3-kinase regulatory subunit alpha, PI3 kinase-associated p85, PI3-kinase subunit p85-alpha, PI3K regulatory subunit alpha, growth factor receptor bound 1, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphatidylinositol 3-kinase-associated p-85 alpha, phosphoinositide-3-kinase regulatory subunit alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), ptdIns-3-kinase regulatory subunit alpha
- HostRabbit
- IsotypeIgG
- Protein IDP27986
- Protein NamePhosphatidylinositol 3-kinase regulatory subunit alpha
- Scientific DescriptionPhosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Shi YJ, Yang CG, Qiao WB, et al. Sacubitril/valsartan attenuates myocardial inflammation, hypertrophy, and fibrosis in rats with heart failure with preserved ejection fraction. Eur J Pharmacol. 2023,961:176170. doi: 10.1016/j.ejphar.2023.176170Read this paper
- Chen J, Sun J, Wang Q, et al. Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis. Front Oncol. 2022,12:825484. doi: 10.3389/fonc.2022.825484Read this paper
- Yeh CC, Liu HM, Lee MC, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022,25(2):pii: 57. doi: 10.3892/mmr.2021.12572.Read this paper
- Lee KT, Chen BC, Liu SC, et al. Nesfatin-1 facilitates IL-1β production in osteoarthritis synovial fibroblasts by suppressing miR-204-5p synthesis through the AP-1 and NF-κB pathways. Aging (Albany NY). 2021,13(18):22490-22501. doi: 10.18632/aging.203559Read this paper
- Chao CC, Lee CW, Chang TM, et al. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). 2020,12(2). doi: 10.3390/cancers12020459Read this paper
- Hu Y, Deng J, Tian K, et al. MiR-8-3p regulates hyperthermia-induced lactate secretion by targeting PPP2R5B in boar Sertoli cells. Mol Reprod Dev. 2019,86(11):1720-1730. doi: 10.1002/mrd.23265Read this paper
- Huang WY, Zou X, Lu FE, et al. Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats. Curr Med Sci. 2018,38(4):704-713. doi: 10.1007/s11596-018-1934-xRead this paper
- Chen PH, Cheng CH, Shih CM, et al. The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. PLoS One. 2016,11(11):e0167096. doi: 10.1371/journal.pone.0167096Read this paper
- Chiu WC, Lee YC, Su YH, et al. The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways. PLoS One. 2016,11(11):e0166453. doi: 10.1371/journal.pone.0166453Read this paper

![ELISA analysis of antigen using GTX60634 PI3 kinase p85 alpha antibody [8C11]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60634/GTX60634_20170912_ELISA_w_23061123_690.webp)
