PI3 kinase p85 alpha antibody [8-2D-4D]

GeneTex

PI3 kinase p85 alpha antibody [8-2D-4D]

9

For IF: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Detects a band of ~ 85 kDa, which corresponds to the predicted molecular weight of PI 3 Kinase. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

8-2D-4D

0.2 mg/ml

Unconjugated

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

AGM7; GRB1; IMD36; p85; p85-ALPHA; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); PI3K regulatory subunit alpha; PI3-kinase subunit p85-alpha; ptdIns-3-kinase regulatory subunit alpha

Mouse

IgG1

Phosphatidylinositol 3-kinase regulatory subunit alpha

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Human, Mouse, Rat

2°C to 8°C

12352203