PIM447 (LGH447)
S7985
CAS Number1210608-43-7
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NamePIM447 (LGH447)
- Delivery Days Customer9
- CAS Number1210608-43-7
- CertificationResearch Use Only
- Scientific DescriptionPIM447 (LGH447) is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3bèta, PKN1, and PKCtau, but at a significantly lower potency with IC50 between 1 and 5 muM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.
- UNSPSC12352200
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