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Pirh2 antibody

GTX117588
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetRCHY1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Pirh2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.88 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25898
  • Target name
    RCHY1
  • Target description
    ring finger and CHY zinc finger domain containing 1
  • Target synonyms
    androgen-receptor N-terminal-interacting protein; ARNIP; CHIMP; CH-rich interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; p53-induced protein with a RING-H2 domain; PIRH2; PRO1996; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; zinc finger protein 363; zinc finger, CHY-type; ZNF363
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96PM5
  • Protein Name
    RING finger and CHY zinc finger domain-containing protein 1
  • Scientific Description
    The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Primate-specific miR-944 activates p53-dependent tumor suppression in human colorectal cancers. Kim YJ et al., 2019 Jan, Cancer Lett
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