Pirh2 antibody
GTX117588
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetRCHY1
Overview
- SupplierGeneTex
- Product NamePirh2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.88 mg/ml
- ConjugateUnconjugated
- Gene ID25898
- Target nameRCHY1
- Target descriptionring finger and CHY zinc finger domain containing 1
- Target synonymsandrogen-receptor N-terminal-interacting protein; ARNIP; CHIMP; CH-rich interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; p53-induced protein with a RING-H2 domain; PIRH2; PRO1996; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; RING finger and CHY zinc finger domain-containing protein 1; RING finger protein 199; RING-type E3 ubiquitin transferase RCHY1; RNF199; ZCHY; zinc finger protein 363; zinc finger, CHY-type; ZNF363
- HostRabbit
- IsotypeIgG
- Protein IDQ96PM5
- Protein NameRING finger and CHY zinc finger domain-containing protein 1
- Scientific DescriptionThe protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Primate-specific miR-944 activates p53-dependent tumor suppression in human colorectal cancers. Kim YJ et al., 2019 Jan, Cancer LettRead more