Pirtobrutinib (LOXO-305)
M10604
CAS Number2101700-15-4
Product group Chemicals
Molecular Weight479.43
Overview
- SupplierAbMole BioScience
- Product NamePirtobrutinib (LOXO-305)
- Delivery Days Customer9
- CAS Number2101700-15-4
- CertificationResearch Use Only
- Molecular FormulaC22H21F4N5O3
- Molecular Weight479.43
- Scientific DescriptionPirtobrutinib (LOXO-305; LY 3527727; RXC-005) is a first-in-class, highly selective, non-covalent, next-generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells.Pirtobrutinib's selectivity for BTK more than 300 times more selective than other 370 kinases. Pirtobrutinib can be used in studies related to chronic lymphocytic leukemia (CLL).
- SMILESCOC1=CC=C(F)C=C1C(=O)NCC2=CC=C(C=C2)C3=N[N](C(C)C(F)(F)F)C(=C3C(N)=O)N
- Storage Instruction2-8°C, sealed
- UNSPSC12352200
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