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Pirtobrutinib (LOXO-305)

M10604
AbMole BioScience
CAS Number2101700-15-4
Product group Chemicals
Molecular Weight479.43
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Pirtobrutinib (LOXO-305)
  • Delivery Days Customer
    9
  • CAS Number
    2101700-15-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C22H21F4N5O3
  • Molecular Weight
    479.43
  • Scientific Description
    Pirtobrutinib (LOXO-305; LY 3527727; RXC-005) is a first-in-class, highly selective, non-covalent, next-generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells.Pirtobrutinib's selectivity for BTK more than 300 times more selective than other 370 kinases. Pirtobrutinib can be used in studies related to chronic lymphocytic leukemia (CLL).
  • SMILES
    COC1=CC=C(F)C=C1C(=O)NCC2=CC=C(C=C2)C3=N[N](C(C)C(F)(F)F)C(=C3C(N)=O)N
  • Storage Instruction
    2-8°C, sealed
  • UNSPSC
    12352200

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