PITX2 Antibody

Cusabio

PITX2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

PITX2

paired like homeodomain 2

all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1; ASGD4; Brx1; homeobox protein PITX2; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; paired-like homeodomain transcription factor 2; pituitary homeobox 2; PTX2; RGS; RIEG; rieg bicoid-related homeobox transcription factor 1; RIEG1; RS; solurshin

Rabbit

IgG

Pituitary homeobox 2

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Human, Rat

-20°C or -80°C

41116161