IHC-P analysis of human colon carcinoma tissue using GTX50309 PKR (phospho Thr451) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
IHC-P analysis of human colon carcinoma tissue using GTX50309 PKR (phospho Thr451) antibody. Left : Primary antibody Right : Primary antibody pre-incubated with the antigen specific peptide
PKR (phospho Thr451) antibody
GTX50309
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEIF2AK2
Overview
- SupplierGeneTex
- Product NamePKR (phospho Thr451) antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5610
- Target nameEIF2AK2
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 2
- Target synonymsdouble stranded RNA activated protein kinase; eIF-2A protein kinase 2; EIF2AK1; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; LEUDEN; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; PRKR; protein kinase R; protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; tyrosine-protein kinase EIF2AK2
- HostRabbit
- IsotypeIgG
- Protein IDP19525
- Protein NameInterferon-induced, double-stranded RNA-activated protein kinase
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203