Western blot analysis of extracts of various cell lines using PLC gamma 1 (PLC gamma 1 (PLCG1)) Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PLC gamma 1 (PLC gamma 1 (PLCG1)) Polyclonal Antibody at 1:1000 dilution.
PLCG1 Polyclonal Antibody
E-AB-62164
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePLCG1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203