Immunofluorescence analysis of HepG2 cells using POLR2A Polyclonal Antibody
POLR2A Polyclonal Antibody
E-AB-60611
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePOLR2A Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
- UNSPSC12352203