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PP2A alpha antibody

Research Use Only
GTX113523
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPPP2CA
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Overview

  • Supplier
    GeneTex
  • Product Name
    PP2A alpha antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.45 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5515
  • Target name
    PPP2CA
  • Target description
    protein phosphatase 2 catalytic subunit alpha
  • Target synonyms
    NEDLBA; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; protein phosphatase 2, catalytic subunit, alpha isozyme; replication protein C; RP-C; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP67775
  • Protein Name
    Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
  • Scientific Description
    This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. Ueda T et al., 2019 Mar, Cell Signal
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  • Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade. Chen YY et al., 2014 Jul 10, Sci Rep
    Read more