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WB analysis of mouse liver tissue lysate (35ug/lane) using GTX50878 PPM1F antibody, N-term.
WB analysis of mouse liver tissue lysate (35ug/lane) using GTX50878 PPM1F antibody, N-term.
WB analysis of mouse liver tissue lysate (35ug/lane) using GTX50878 PPM1F antibody, N-term.

PPM1F antibody, N-term

GTX50878
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPPM1F
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Overview

  • Supplier
    GeneTex
  • Product Name
    PPM1F antibody, N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID9647
  • Target name
    PPM1F
  • Target description
    protein phosphatase, Mg2+/Mn2+ dependent 1F
  • Target synonyms
    Ca(2+)/calmodulin-dependent protein kinase phosphatase; CaM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFEM-2; partner of PIX 2; POPX2; PP2C phosphatase; protein fem-2 homolog; protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP49593
  • Protein Name
    Protein phosphatase 1F
  • Scientific Description
    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203