WB analysis of various samples using GTX00857 Prion Protein (PrP) antibody [7A1]. Lane 1 : Prion protein was overexpressed in RK13 cells Lane 2 : Vector only in RK13 cells Lane 3 : RK13 cells only
WB analysis of various samples using GTX00857 Prion Protein (PrP) antibody [7A1]. Lane 1 : Prion protein was overexpressed in RK13 cells Lane 2 : Vector only in RK13 cells Lane 3 : RK13 cells only
Prion Protein (PrP) antibody [7A1]
GTX00857
Overview
- SupplierGeneTex
- Product NamePrion Protein (PrP) antibody [7A1]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Mouse.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID7A1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5621
- Target namePRNP
- Target descriptionprion protein
- Target synonymsalternative prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; p27-30; prion-related protein; PRIP; PrP; PrP27-30; PrP33-35C; PrPc
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203