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ProductsBack/Prion Protein (PrP) antibody [EM-20]
WB analysis of Creutzfeld-Jakob disease (CJD) negative (lane 1, 2) and CJD positive (lane 3, 4) human brain material using GTX80160 Prion Protein (PrP) antibody [EM-20]. CJD positive patient has proteinase K resistent prion protein. Lane 1, 4 : With proteinase K treatment Lane 2, 3 : Without proteinase K treatment
WB analysis of Creutzfeld-Jakob disease (CJD) negative (lane 1, 2) and CJD positive (lane 3, 4) human brain material using GTX80160 Prion Protein (PrP) antibody [EM-20]. CJD positive patient has proteinase K resistent prion protein. Lane 1, 4 : With proteinase K treatment Lane 2, 3 : Without proteinase K treatment
WB analysis of Creutzfeld-Jakob disease (CJD) negative (lane 1, 2) and CJD positive (lane 3, 4) human brain material using GTX80160 Prion Protein (PrP) antibody [EM-20]. CJD positive patient has proteinase K resistent prion protein. Lane 1, 4 : With proteinase K treatment Lane 2, 3 : Without proteinase K treatment

Prion Protein (PrP) antibody [EM-20]

Research Use Only
GTX80160
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetPRNP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Prion Protein (PrP) antibody [EM-20] - Orthogonal Validated
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is suitable for discrimination between normal cellular prion protein (PrPc) and its conformationally changed form (PrPSc) prion protein.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    EM-20
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID5621
  • Target name
    PRNP
  • Target description
    prion protein
  • Target synonyms
    alternative prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; p27-30; prion-related protein; PRIP; PrP; PrP27-30; PrP33-35C; PrPc
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDF7VJQ1
  • Protein Name
    Alternative prion protein
  • Scientific Description
    The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203