Prion Protein (PrP) antibody
GTX101063
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPRNP
Overview
- SupplierGeneTex
 - Product NamePrion Protein (PrP) antibody
 - Delivery Days Customer9
 - Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
 - ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
 - CertificationResearch Use Only
 - ClonalityPolyclonal
 - Concentration0.36 mg/ml
 - ConjugateUnconjugated
 - Gene ID5621
 - Target namePRNP
 - Target descriptionprion protein
 - Target synonymsalternative prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; major prion protein; p27-30; prion-related protein; PRIP; PrP; PrP27-30; PrP33-35C; PrPc
 - HostRabbit
 - IsotypeIgG
 - Protein IDF7VJQ1
 - Protein NameAlternative prion protein
 - Scientific DescriptionThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
 - Storage Instruction-20°C or -80°C,2°C to 8°C
 - UNSPSC12352203
 

![WB analysis of Creutzfeld-Jakob disease (CJD) negative (lane 1, 2) and CJD positive (lane 3, 4) human brain material using GTX80160 Prion Protein (PrP) antibody [EM-20]. CJD positive patient has proteinase K resistent prion protein. Lane 1, 4 : With proteinase K treatment Lane 2, 3 : Without proteinase K treatment](https://www.genetex.com/upload/website/prouct_img/normal/GTX80160/GTX80160_20191025_AP_001_399_w_23061322_897.webp)

![WB analysis of various samples using GTX00856 Prion Protein (PrP) antibody [2C5-5]. Lane 1 : Prion protein was overexpressed in RK13 cells Lane 2 : Vector only in RK13 cells Lane 3 : RK13 cells only](https://www.genetex.com/upload/website/prouct_img/normal/GTX00856/GTX00856_20200406_AP_001_56_w_23053121_239.webp)


