Cross-linked ChIP was performed with NIH3T3 chromatin extract and 5 μg of either control rabbit IgG or anti-PRMT7 antibody. The precipitated DNA was detected by PCR with primer set targeting to Apex2.
Cross-linked ChIP was performed with NIH3T3 chromatin extract and 5 μg of either control rabbit IgG or anti-PRMT7 antibody. The precipitated DNA was detected by PCR with primer set targeting to Apex2.
PRMT7 antibody
GTX116570
ApplicationsImmunoFluorescence, ImmunoPrecipitation, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPRMT7
Overview
- SupplierGeneTex
- Product NamePRMT7 antibody
- Delivery Days Customer9
- Application Supplier NoteICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID54496
- Target namePRMT7
- Target descriptionprotein arginine methyltransferase 7
- Target synonymsSBIDDS, protein arginine N-methyltransferase 7, [Myelin basic protein]-arginine N-methyltransferase PRMT7, histone-arginine N-methyltransferase PRMT7
- HostRabbit
- IsotypeIgG
- Protein IDQ9NVM4
- Protein NameProtein arginine N-methyltransferase 7
- Scientific DescriptionArginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing (Miranda et al., 2004 [PubMed 15044439]).[supplied by OMIM]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Jeong HJ, Lee SJ, Lee HJ, et al. Prmt7 promotes myoblast differentiation via methylation of p38MAPK on arginine residue 70. Cell Death Differ. 2020,27(2):573-586. doi: 10.1038/s41418-019-0373-yRead this paper
- Jeong HJ, Lee HJ, Vuong TA, et al. Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity. Diabetes. 2016,65(7):1868-82. doi: 10.2337/db15-1500Read this paper
Datasheet
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