Prostaglandin J2
ORB1983460
CAS Number60203-57-8
Product group Chemicals
Estimated Purity98.00%
Molecular Weight334.45
Overview
- SupplierBiorbyt
- Product NameProstaglandin J2 [60203-57-8]
- Delivery Days Customer10
- CAS Number60203-57-8
- CertificationResearch Use Only
- Estimated Purity98.00%
- Molecular FormulaC20H30O4
- Molecular Weight334.45
- Scientific DescriptionProstaglandin J2 (PGJ2), a derivative of Prostaglandin D2 (PGD2), serves as a potent agonist for PGD2 receptors (DP), exhibiting affinity constants (K i) of 0.9 nM and 6.6 nM for hDP and hCRTH2 receptors, respectively. It activates cyclic AMP production with an EC50 of 1.2 nM, induces oxidative stress, neuronal apoptosis, and promotes the accumulation of ubiquitinated (Ub) proteins. Notably, PGJ2s neurotoxic properties are implicated in the progression of neurodegenerative diseases such as Alzheimers (AD) and Parkinsons (PD) [1] [2] [3] [4].
- SMILESCCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)C=CC1=O
- Storage Instruction-20°C
- UNSPSC12352200
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Product group Chemicals
CAS Number60203-57-8
Molecular Weight334.45
- SizePrice
Product group Chemicals
Prostaglandin J2HY-113366
CAS Number60203-57-8
Estimated Purity98.10
Molecular Weight334.45
- SizePrice
