Protein C antibody [N2C3]
GTX109504
Overview
- SupplierGeneTex
- Product NameProtein C antibody [N2C3]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5624
- Target namePROC
- Target descriptionprotein C, inactivator of coagulation factors Va and VIIIa
- Target synonymsactivated protein C; anticoagulant protein C; APC; autoprothrombin IIA; blood coagulation factor XIV; PC; prepro-protein C; PROC1; Protein C-Nagoya; THPH3; THPH4; type I protein C; vitamin K-dependent protein C
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, activated protein C (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203