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Proteins / Signaling Molecules

This product group contains both native proteins and recombinant proteins expressed and purified from bacterial, insect and mammalian expression systems. Bio-Connect also offers fusion proteins, peptides, enzymes, bacterial and viral proteins, hormones and growth factors. Furthermore, it includes chemokines and cytokines, collagenases, albumins, globulins, blood/plasma related proteins and more.

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Protein structure of IL-2 (human) (Switch-2) (monomeric):Fc-KIH (human) (rec.) (Prod. No. AG-40B-0234).
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-2 (human) (Switch-2) (monomeric):Fc-KIH (human) (rec.)AG-40B-0234
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Protein structure of IL-23 (mouse):Fc-KIH (human) (rec.) (Prod. No. AG-40B-0235) containing a single heterodimer.
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-23 (mouse):Fc-KIH (human) (rec.)AG-40B-0235
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IL-27 (mouse):Fc-KIH (human) (rec.) (#AG-40B-0236) (Heterodimer) is more active than an IL-27 (mouse):Fc from a competitor (Dimer of Heterodimer). Method: 5x104 HepG2 cells (a human hepatocellular carcinoma cell line) are treated with IL-27 (mouse):Fc-KIH (human) (rec.) (#AG-40B-0236, AdipoGen) or from IL-27 (mouse):Fc (human) from a competitor at different concentrations indicated on the figure for 15 minutes. Cells are lysed and cell extracts are separated by SDS-PAGE (12.5%) under reducing conditions, transferred to nitrocellulose overnight and incubated with anti-Phospho-Stat3 (Tyr705) (human), Rabbit Monoclonal (RM261) (#REV-31-1142-00) (1/1000) or anti-Stat3, Rabbit Monoclonal (RM465) (#REV-31-1357-00) (1/1000). After the addition of an anti-rabbit secondary antibody coupled to HRP (1/10000), proteins are visualized by a chemiluminescence detection system. A) Western Blot, B) Quantification figure of the Western Blot.
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-27 (mouse):Fc-KIH (human) (rec.)AG-40B-0236
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
VSTM5 (human):Fc (human) (rec.) (non-lytic)AG-40B-0237
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Protein structure of IL-7 (human) (monomeric):Fc-KIH (human) (rec.) (Prod. No. AG-40B-0238).
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-7 (human) (monomeric):Fc-KIH (human) (rec.)AG-40B-0238
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
VSTM5 (mouse):Fc (mouse) (rec.) (non-lytic)AG-40B-0239
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-12 (mouse):Fc-KIH (human) (rec.)AG-40B-0240
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IL-38 (aa 1-152) (human) (monomeric):Fc-KIH (human) (rec.)AG-40B-0241
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Fc (human):Grancalcin (human) (rec.)AG-40B-0242
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Flagellin (AG-40B-0243) activates TLR5 in vivo. Method: Mice WT are injected i.v. with indicated doses of Flagellin (Prod. No. AG-40B-0243). After 2 hours, levels of CCL20 and IL-6 in the serum were measured by ELISA. As a control, mice TLR5 -/- have been injected i.v. with 10microg of Flagellin (Prod. No. AG-40B-0243), but no expression of CCL20 and IL-6 could be observed (not shown).
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Flagellin (rec.) (untagged) (highly active)AG-40B-0243
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Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
IGFL1 (human) (rec.)AG-40B-0244
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Protein structure of Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.) (Prod. No. AG-40B-0245).
Product group Proteins / Signaling Molecules
AdipoGen Life Sciences
Fc (LALA-PG)-KIH (human):GDF15 (mouse) (rec.)AG-40B-0245
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