Prothrombin antibody [5013]

GeneTex

Prothrombin antibody [513]

9

Recognises fragment 2 region of Prothrombin

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

5013

5 mg/ml

Unconjugated

F2

coagulation factor II, thrombin

prepro-coagulation factor II; prothrombin; prothrombin B-chain; PT; RPRGL2; THPH1; thrombin factor II

Mouse

IgG2a

Prothrombin

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Human

-20°C or -80°C,2°C to 8°C

12352203