PSMC3 antibody

GeneTex

PSMC3 antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

PSMC3

proteasome 26S subunit, ATPase 3

DCIDP, RPT5, TBP1, 26S proteasome regulatory subunit 6A, 26S protease regulatory subunit 6A, 26S proteasome AAA-ATPase subunit RPT5, Tat-binding protein 1, human immunodeficiency virus tat transactivator binding protein-1, proteasome (prosome, macropain) 26S subunit, ATPase, 3, proteasome subunit P50, testicular secretory protein Li 42

Rabbit

IgG

26S proteasome regulatory subunit 6A

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203