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Pyridone 6

M3737
AbMole BioScience
CAS Number457081-03-7
Product group Chemicals
Estimated Purity>98.0%
Molecular Weight309.34
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Pyridone 6
  • Delivery Days Customer
    9
  • CAS Number
    457081-03-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >98.0%
  • Molecular Formula
    C18H16FN3O
  • Molecular Weight
    309.34
  • Scientific Description
    Pyridone 6 is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk 2 (IC50 = 1 nM) (Janus protein tyrosine kinases).
  • SMILES
    CC(C)(C)C1=NC2=C([NH]1)C3=CC=C(F)C=C3C4=C2C=CNC4=O
  • UNSPSC
    12352200