Rabbit anti-BCL-x Polyclonal Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
RD70030A
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBCL2L1
Overview
- SupplierReddot Biotech
- Product NameRabbit anti-BCL-x Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID598
- Target nameBCL2L1
- Target descriptionBCL2 like 1
- Target synonymsapoptosis regulator Bcl-X; BCL2L; bcl-2-like protein 1; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52
- HostRabbit
- IsotypeIgG
- Scientific DescriptionBCL2L1 is a member of he BCL-2 protein family. BCL2L1 is expressed as two distinct isoforms, Bcl-xL and Bcl-xS, and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator. This antibody can recognize Bcl-XL, Bcl-XS and Bcl-X(Beta).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203