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Rabbit anti Human PINK1 (G309D Mutant)

Research Use Only
X2761P
Nordic-MUbio
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
€ 332,00
100 ug
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Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Rabbit anti Human PINK1 (G309D Mutant)
  • Delivery Days Customer
    7
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    Western Blotting;Enzyme Immunoassay;Western Blotting;Immunohistochemistry;Enzyme Immunoassay
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Concentration
    See vial for concentration
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    PTEN-induced putative kinase protein 1
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Synthetic peptide derived from a mutant form of the human PINK1 protein
  • Storage Instruction
    Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
  • UNSPSC
    12352203

References

  • 1. Matsuda, N., et al. ‘PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.’ J. Cell. Biol., 189, 211-221 (2010) 2. Vives-Bauza, C., et al. ‘PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.’ Proc. Natl. Acad. Sci. USA, 107, 378-383 (2010) 3. Valente, E.M., et al. ‘PINK1 mutations are associated with sporadic early-onset parkinsonism.’ Ann. Neurol., 56, 336-341 (2004) 4. Geisler, S., et al. ‘The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations.’ Autophagy, 6, 871-878 (2010) 5. Valente, E.M., et al. ‘Hereditary early-onset Parkinson's disease caused by mutations in PINK1.’ Science, 304, 1158-1160 (2004) 6. Silvestri, L., et al. ‘Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.’ Hum. Mol. Genet., 14, 3477-3492 (2005)