Bio-Connect

Rabbit anti Human SMase Activation Associated Factor

Research Use Only
X2354P
Nordic-MUbio
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNSMAF
Price on request
100 ug
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Rabbit anti Human SMase Activation Associated Factor
  • Delivery Days Customer
    7
  • Application Supplier Note
    Antibody can be used for Western blotting (1:400 starting dilution) and immunohistochemistry (10-15 microg/ml). Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    Western Blotting;Western Blotting;Immunohistochemistry
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Gene ID8439
  • Target name
    NSMAF
  • Target description
    neutral sphingomyelinase activation associated factor
  • Target synonyms
    factor associated with neutral sphingomyelinase activation; factor associated with N-SMase activation; FAN; GRAMD5; neutral sphingomyelinase (N-SMase) activation associated factor; protein FAN
  • Host
    Rabbit
  • Protein IDQ8IW26
  • Protein Name
    Protein FAN
  • Scientific Description
    nSMAF; Neutral sphingomyelinase (N-SMase) activation associated factor
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Synthetic peptide derived from human NSMAF protein.
  • UNSPSC
    12352203

References

  • 1. O’Brien, N.W., et al. 'Factor associated with neutral sphingomyelinase activation and its role in cardiac cell death.' Circ Res. 2003 Apr 4;92(6):589-91. 2. Segui, B., et al. 'CD40 Signals apoptosis through FAN-regulated activation of the sphinogmyelin-ceramide pathway.' J Biol Chem. 1999; 274: 37251–37258 3. Adam-Klages, S., et al. 'FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase.' Cell. 1996; 86: 937–947. 4. Segui, B., et al. 'Involvement of FAN in TNF-induced apoptosis.' J Clin Invest. 2001; 108: 143–151.