Rabbit anti Human SMO (Smoothened Homolog)
X2333P
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetSMO
Overview
- SupplierNordic-MUbio
- Product NameRabbit anti Human SMO (Smoothened Homolog)
- Delivery Days Customer7
- Application Supplier NoteAntibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityPolyclonal
- Gene ID6608
- Target nameSMO
- Target descriptionsmoothened, frizzled class receptor
- Target synonymsCRJS; frizzled family member 11; FZD11; Gx; PHLS; protein Gx; seven transmembrane helix receptor; SMOH; smoothened homolog; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
- HostRabbit
- IsotypeIgG
- Protein IDQ99835
- Protein NameSmoothened homolog
- Scientific DescriptionSmoothened homolog [Precursor], SMO, Gx protein, SMO, SMOH
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteSynthetic peptide derived from the human SMO protein
- UNSPSC12352203
References
- 1. Stone, D.M., et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.; Nature 384:129-134(1996). 2. Xie, J., et al. Activating Smoothened mutations in sporadic basal-cell carcinoma.; Nature 391:90-92(1998). 3. Liu, Y., et al. 'Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation.' Genes Dev. 2007 Aug 1;21(15):1949-63. 4. Moraea, R.C., et al. 'Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia.' Development. 2007 Mar;134(6):1231-42. 5. Ruiz-Gomez, A., et al. 'The cell biology of Smo signalling and its relationships with GPCRs.' Biochim Biophys Acta. 2007 Apr;1768(4):901-12.