(Rac)-SAG
HY-12848A
Overview
- SupplierMedChem Express
- Product Name(Rac)-SAG [364590-63-6]
- Delivery Days Customer14
- CAS Number364590-63-6
- CertificationResearch Use Only
- Molecular FormulaC28H28ClN3OS
- Molecular Weight490.06
- Scientific Description(Rac)-SAG is an isoform of SAG (HY-12848). SAG is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine (HY-17024) inhibition of Smo [1] [2] [3] .
- SMILESO=C(C1=C(Cl)C2=CC=CC=C2S1)N(C3CCC(NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4
- UNSPSC12352200