(Rac)-SAG [364590-63-6]

TargetMol Chemicals

(Rac)-SAG [364590-63-6]

16

364590-63-6

Research Use Only

C28H28ClN3OS

490.06

(Rac)-SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC50 = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamines inhibition of Smo [1] [2] [3].

N(C(=O)C1=C(Cl)C=2C(S1)=CC=CC2)(CC3=CC(=CC=C3)C=4C=CN=CC4)C5CCC(NC)CC5

-20°C

12352200