SAG . dihydrochloride (water soluble) [364590-63-6]

AdipoGen Life Sciences

SAG . dihydrochloride (water soluble)

10

364590-63-6

Research Use Only

>98%

C28H28ClN3OS . 2HCl . 3H2O

490.1 . 72.9 . 54.0

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable G-Protein-Coupled Receptor (GPCR) smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro. - Chemical. CAS: 912545-86-9 and 364590-63-6 (both free base). Formula: C28H28ClN3OS . 2HCl . 3H2O. MW: 490.1 . 72.9 . 54.0. Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

O.CNC1CCC(CC1)N(CC1=CC(=CC=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=CC=CC=C2S1

-20°C,2°C to 8°C

12352200