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Rac1 antibody

GTX100761
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAC1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Rac1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.79 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5879
  • Target name
    RAC1
  • Target description
    Rac family small GTPase 1
  • Target synonyms
    MIG5, MRD48, Rac-1, TC-25, p21-Rac1, ras-related C3 botulinum toxin substrate 1, cell migration-inducing gene 5 protein, ras-like protein TC25, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP63000
  • Protein Name
    Ras-related C3 botulinum toxin substrate 1
  • Scientific Description
    The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hsiao YW, Chi JY, Li CF, et al. Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers. Clin Transl Med. 2022,12(1):e724. doi: 10.1002/ctm2.724
    Read this paper
  • Ito H, Morishita R, Mizuno M, et al. Rho family GTPases, Rac and Cdc42, control the localization of neonatal dentate granule cells during brain development. Hippocampus. 2019,29(7):569-578. doi: 10.1002/hipo.23047
    Read this paper
  • Buczak K, Ori A, Kirkpatrick JM, et al. Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). Mol Cell Proteomics. 2018,17(4):810-825. doi: 10.1074/mcp.RA117.000189
    Read this paper
  • Chen ML, Tsai FM, Lee MC, et al. Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway. Prog Neuropsychopharmacol Biol Psychiatry. 2016,71:14-26. doi: 10.1016/j.pnpbp.2016.06.003
    Read this paper
  • Wang SM, Hsu JC, Ko CY, et al. Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury. Mol Neurobiol. 2016,53(9):5912-5927. doi: 10.1007/s12035-015-9486-6
    Read this paper
  • Toyo-oka K, Wachi T, Hunt RF, et al. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014,34(36):12168-81. doi: 10.1523/JNEUROSCI.2513-13.2014
    Read this paper
  • Katz E, Sims AH, Sproul D, et al. Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget. 2012,3(6):608-19.
    Read this paper