Rac1 antibody
GTX100761
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRAC1
Overview
- SupplierGeneTex
- Product NameRac1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.79 mg/ml
- ConjugateUnconjugated
- Gene ID5879
- Target nameRAC1
- Target descriptionRac family small GTPase 1
- Target synonymsMIG5, MRD48, Rac-1, TC-25, p21-Rac1, ras-related C3 botulinum toxin substrate 1, cell migration-inducing gene 5 protein, ras-like protein TC25, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
- HostRabbit
- IsotypeIgG
- Protein IDP63000
- Protein NameRas-related C3 botulinum toxin substrate 1
- Scientific DescriptionThe protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hsiao YW, Chi JY, Li CF, et al. Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers. Clin Transl Med. 2022,12(1):e724. doi: 10.1002/ctm2.724Read this paper
- Ito H, Morishita R, Mizuno M, et al. Rho family GTPases, Rac and Cdc42, control the localization of neonatal dentate granule cells during brain development. Hippocampus. 2019,29(7):569-578. doi: 10.1002/hipo.23047Read this paper
- Buczak K, Ori A, Kirkpatrick JM, et al. Spatial Tissue Proteomics Quantifies Inter- and Intratumor Heterogeneity in Hepatocellular Carcinoma (HCC). Mol Cell Proteomics. 2018,17(4):810-825. doi: 10.1074/mcp.RA117.000189Read this paper
- Chen ML, Tsai FM, Lee MC, et al. Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway. Prog Neuropsychopharmacol Biol Psychiatry. 2016,71:14-26. doi: 10.1016/j.pnpbp.2016.06.003Read this paper
- Wang SM, Hsu JC, Ko CY, et al. Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury. Mol Neurobiol. 2016,53(9):5912-5927. doi: 10.1007/s12035-015-9486-6Read this paper
- Toyo-oka K, Wachi T, Hunt RF, et al. 14-3-3ε and ζ regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014,34(36):12168-81. doi: 10.1523/JNEUROSCI.2513-13.2014Read this paper
- Katz E, Sims AH, Sproul D, et al. Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget. 2012,3(6):608-19.Read this paper





