RAGE antibody [8D11]
GTX52973
ApplicationsFunctional Assay, Western Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetAGER
Overview
- SupplierGeneTex
- Product NameRAGE antibody [8D11]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFunctional Assay, Western Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID8D11
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID177
- Target nameAGER
- Target descriptionadvanced glycosylation end-product specific receptor
- Target synonymsadvanced glycosylation end product-specific receptor; RAGE; receptor for advanced glycation end-products variant 20; SCARJ1; sRAGE
- HostMouse
- IsotypeIgG2
- Protein IDQ15109
- Protein NameAdvanced glycosylation end product-specific receptor
- Scientific DescriptionThe advanced glycosylation end product (AGE) receptor encoded by this gene is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimers disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID:18089847). [provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Advanced glycation end-products increase lipocalin 2 expression in human oral epithelial cells. Kido R et al., 2020 Aug, J Periodontal ResRead more