RALA Antibody, FITC conjugated
CSB-PA019296LC01HU
ReactivityHuman
Product group Antibodies
TargetRALA
Overview
- SupplierCusabio
- Product NameRALA Antibody, FITC conjugated
- Delivery Days Customer20
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateFITC
- Gene ID5898
- Target nameRALA
- Target descriptionRAS like proto-oncogene A
- Target synonymsHINCONS; RAL; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; RAS-like protein A; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)
- HostRabbit
- IsotypeIgG
- Protein IDP11233
- Protein NameRas-related protein Ral-A
- Scientific DescriptionMultifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203