RAP1A antibody [HL2415]

GeneTex

RAP1A antibody [HL2415]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

HL2415

1 mg/ml

Unconjugated

RAP1A

RAP1A, member of RAS oncogene family

C21KG, G-22K, KREV-1, KREV1, RAP1, SMGP21, ras-related protein Rap-1A, GTP-binding protein smg p21A, Ras-related protein Krev-1

Rabbit

IgG

Ras-related protein Rap-1A

This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203