IHC-P analysis of human colon carcinoma tissue using GTX17119 Rb antibody [1F8] (ready-to-use).
IHC-P analysis of human colon carcinoma tissue using GTX17119 Rb antibody [1F8] (ready-to-use).
Rb antibody [1F8] (ready-to-use)
GTX17119
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetRB1
Overview
- SupplierGeneTex
- Product NameRb antibody [1F8] (ready-to-use)
- Delivery Days Customer9
- Application Supplier NoteIHC-P: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1F8
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID5925
- Target nameRB1
- Target descriptionRB transcriptional corepressor 1
- Target synonymsexon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p105-Rb; p110-RB1; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; RB; retinoblastoma 1; retinoblastoma suspectibility protein; retinoblastoma-associated protein
- HostMouse
- IsotypeIgG1
- Protein IDP06400
- Protein NameRetinoblastoma-associated protein
- Scientific DescriptionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203