Rb (phospho Ser780) antibody
GTX133893
ApplicationsWestern Blot
Product group Antibodies
TargetRB1
Overview
- SupplierGeneTex
- Product NameRb (phospho Ser780) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.09 mg/ml
- ConjugateUnconjugated
- Gene ID5925
- Target nameRB1
- Target descriptionRB transcriptional corepressor 1
- Target synonymsOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110, retinoblastoma-associated protein, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, retinoblastoma 1, retinoblastoma suspectibility protein
- HostRabbit
- IsotypeIgG
- Protein IDP06400
- Protein NameRetinoblastoma-associated protein
- Scientific DescriptionThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Effects of Sclareol Against Small Cell Lung Carcinoma and the Related Mechanism: In Vitro and In Vivo Studies. Chen HL et al., 2020 Sep, Anticancer ResRead more


![WB analysis of HL-60 cells treated with camptothecin for 24 hours using GTX13905 Rb cleaved antibody [172C1094].](https://www.genetex.com/upload/website/prouct_img/normal/GTX13905/GTX13905_1065_WB_w_23060620_313.webp)
![IHC-P analysis of human colon carcinoma tissue using GTX17119 Rb antibody [1F8] (ready-to-use).](https://www.genetex.com/upload/website/prouct_img/normal/GTX17119/GTX17119_20191203_IHC-P_23_w_23060620_593.webp)