ProductsBack/RNase H1 antibody [N2C3]

RNase H1 antibody [N2C3]

Name: RNase H1 antibody [N2C3]
SKU: GTX117624_G10
Availability: BackOrder

GTX117624

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetRNASEH1

Overview

Supplier
GeneTex
Product Name
RNase H1 antibody [N2C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.3 mg/ml
Conjugate
Unconjugated
Gene ID246243
Target name
RNASEH1
Target description
ribonuclease H1
Target synonyms
H1RNA, PEOB2, RNH1, ribonuclease H1, ribonuclease H type II
Host
Rabbit
Isotype
IgG
Protein IDO60930
Protein Name
Ribonuclease H1
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Menon S, Breese MR, Lin YP, et al. FET fusion oncoproteins disrupt physiologic DNA repair networks and induce ATR synthetic lethality in cancer. Res Sq. 2023,:pii: rs.3.rs-2869150. doi: 10.21203/rs.3.rs-2869150/v1.
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Menon S, Gracilla D, Breese MR, et al. FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. bioRxiv. 2025,:pii: 2023.04.30.538578. doi: 10.1101/2023.04.30.538578.
Read this paper
Guh CY, Shen HJ, Chen LW, et al. XPF activates break-induced telomere synthesis. Nat Commun. 2022,13(1):5781. doi: 10.1038/s41467-022-33428-0
Read this paper
Silva B, Pentz R, Figueira AM, et al. FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops. Nat Commun. 2019,10(1):2253. doi: 10.1038/s41467-019-10179-z
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Lee YW, Arora R, Wischnewski H, et al. TRF1 participates in chromosome end protection by averting TRF2-dependent telomeric R loops. Nat Struct Mol Biol. 2018,25(2):147-153. doi: 10.1038/s41594-017-0021-5
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Arora R, Lee Y, Wischnewski H, et al. RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells. Nat Commun. 2014,5:5220. doi: 10.1038/ncomms6220
Read this paper