Western Blot Positive WB detected in: Hela whole cell lysate All lanes: ROBO1 antibody at 3.2microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 181, 182, 177, 176, 170 kDa Observed band size: 181 kDa
Western Blot Positive WB detected in: Hela whole cell lysate All lanes: ROBO1 antibody at 3.2microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 181, 182, 177, 176, 170 kDa Observed band size: 181 kDa
ROBO1 Antibody
CSB-PA896760LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
TargetROBO1
Overview
- SupplierCusabio
- Product NameROBO1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6091
- Target nameROBO1
- Target descriptionroundabout guidance receptor 1
- Target synonymsdeleted in U twenty twenty; DUTT1; roundabout homolog 1; roundabout, axon guidance receptor, homolog 1; SAX3
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6N7
- Protein NameRoundabout homolog 1
- Scientific DescriptionReceptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development (PubMed:10102268, PubMed:24560577). Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA (PubMed:26529257). May be required for lung development (By similarity).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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References
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