ROBO1 antibody
GTX114103
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityChicken, Human, Mouse
TargetROBO1
Overview
- SupplierGeneTex
- Product NameROBO1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.26 mg/ml
- ConjugateUnconjugated
- Gene ID6091
- Target nameROBO1
- Target descriptionroundabout guidance receptor 1
- Target synonymsCPHD8, DUTT1, NORS, NYS8, SAX3, roundabout homolog 1, deleted in U twenty twenty, roundabout, axon guidance receptor, homolog 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6N7
- Protein NameRoundabout homolog 1
- Scientific DescriptionBilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityChicken, Human, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yang T, Huang H, Shao Q, et al. miR-92 Suppresses Robo1 Translation to Modulate Slit Sensitivity in Commissural Axon Guidance. Cell Rep. 2018,24(10):2694-2708.e6. doi: 10.1016/j.celrep.2018.08.021Read this paper
- Perez-Ortiz AC, Ramírez I, Cruz-López JC, et al. Pharmacogenetics of response to neoadjuvant paclitaxel treatment for locally advanced breast cancer. Oncotarget. 2017,8(63):106454-106467. doi: 10.18632/oncotarget.22461Read this paper
- Choi YJ, Yoo NJ, Lee SH. Down-regulation of ROBO2 expression in prostate cancers. Pathol Oncol Res. 2014,20(3):517-9. doi: 10.1007/s12253-013-9722-1Read this paper






