ROCK2 (phospho Ser1366) antibody
GTX122651
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetROCK2
Overview
- SupplierGeneTex
- Product NameROCK2 (phospho Ser1366) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID9475
- Target nameROCK2
- Target descriptionRho associated coiled-coil containing protein kinase 2
- Target synonymsROCK-II, rho-associated protein kinase 2, p164 ROCK-2, rho-associated, coiled-coil-containing protein kinase II
- HostRabbit
- IsotypeIgG
- Protein IDO75116
- Protein NameRho-associated protein kinase 2
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Sequeira MK, Swanson AM, Kietzman HW, et al. Cocaine and habit training cause dendritic spine rearrangement in the prelimbic cortex. iScience. 2023,26(4):106240. doi: 10.1016/j.isci.2023.106240Read this paper
- Sánchez-de la Torre A, Aguado T, Huerga-Gómez A, et al. Cannabinoid CB(1) receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice. Cell Death Dis. 2022,13(7):585. doi: 10.1038/s41419-022-05032-zRead this paper
- Zheng H, Li X, Zeng X, et al. TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner. Acta Pharm Sin B. 2021,11(12):3994-4007. doi: 10.1016/j.apsb.2021.04.013Read this paper
- Romano R, Calcagnile M, Margiotta A, et al. RAB7A Regulates Vimentin Phosphorylation through AKT and PAK. Cancers (Basel). 2021,13(9). doi: 10.3390/cancers13092220Read this paper
- Wei L, Surma M, Yang Y, et al. ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice. FASEB J. 2020,34(1):474-493. doi: 10.1096/fj.201901174RRRead this paper
- Marceaux C, Petit D, Bertoglio J, et al. Phosphorylation of ARHGAP19 by CDK1 and ROCK regulates its subcellular localization and function during mitosis. J Cell Sci. 2018,131(5):pii: jcs208397. doi: 10.1242/jcs.208397.Read this paper
- Lu DH, Hsu CC, Huang SW, et al. ARHGEF10 knockout inhibits platelet aggregation and protects mice from thrombus formation. J Thromb Haemost. 2017,15(10):2053-2064. doi: 10.1111/jth.13799Read this paper
- Wang W, Jia Y, Pham DT, et al. Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus. Cereb Cortex. 2018,28(7):2253-2266. doi: 10.1093/cercor/bhx126Read this paper
- Tseng TL, Chen MF, Liu CH, et al. Induction of endothelium-dependent constriction of mesenteric arteries in endotoxemic hypotensive shock. Br J Pharmacol. 2016,173(7):1179-95. doi: 10.1111/bph.13415Read this paper
- Xiao Y, Lin VY, Ke S, et al. 14-3-3τ promotes breast cancer invasion and metastasis by inhibiting RhoGDIα. Mol Cell Biol. 2014,34(14):2635-49.Read this paper
Datasheet
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