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RPB2 antibody [N1], N-term

GTX102535
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPOLR2B
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPB2 antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5431
  • Target name
    POLR2B
  • Target description
    RNA polymerase II subunit B
  • Target synonyms
    DNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; DNA-directed RNA polymerase II subunit RPB2; hRPB140; POL2RB; polymerase (RNA) II (DNA directed) polypeptide B, 140kDa; polymerase (RNA) II subunit B; RNA polymerase II second largest subunit; RNA polymerase II subunit 2; RNA polymerase II subunit B2; RPB2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP30876
  • Protein Name
    DNA-directed RNA polymerase II subunit RPB2
  • Scientific Description
    This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages.
    Read more
  • Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4. Hoeksema MA et al., 2021 Jun, Sci Adv
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  • Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Joensson ME et al., 2019 Jul 18, Nat Commun
    Read more
  • Transcription Elongation Can Affect Genome 3D Structure. Heinz S et al., 2018 Sep 6, Cell
    Read more