RPB2 antibody [N1], N-term
GTX102535
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetPOLR2B
Overview
- SupplierGeneTex
- Product NameRPB2 antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.32 mg/ml
- ConjugateUnconjugated
- Gene ID5431
- Target namePOLR2B
- Target descriptionRNA polymerase II subunit B
- Target synonymsDNA-directed RNA polymerase II 140 kDa polypeptide; DNA-directed RNA polymerase II subunit B; DNA-directed RNA polymerase II subunit RPB2; hRPB140; POL2RB; polymerase (RNA) II (DNA directed) polypeptide B, 140kDa; polymerase (RNA) II subunit B; RNA polymerase II second largest subunit; RNA polymerase II subunit 2; RNA polymerase II subunit B2; RPB2
- HostRabbit
- IsotypeIgG
- Protein IDP30876
- Protein NameDNA-directed RNA polymerase II subunit RPB2
- Scientific DescriptionThis gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages.Read more
- Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4. Hoeksema MA et al., 2021 Jun, Sci AdvRead more
- Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Joensson ME et al., 2019 Jul 18, Nat CommunRead more
- Transcription Elongation Can Affect Genome 3D Structure. Heinz S et al., 2018 Sep 6, CellRead more