Bio-Connect

RPB2 antibody [N1], N-term

GTX102535
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPOLR2B
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    RPB2 antibody [N1], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5431
  • Target name
    POLR2B
  • Target description
    RNA polymerase II subunit B
  • Target synonyms
    POL2RB, RPB2, hRPB140, DNA-directed RNA polymerase II subunit RPB2, 3'-5' exoribonuclease, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II second largest subunit, RNA polymerase II subunit 2, RNA polymerase II subunit B2, RNA-directed RNA polymerase II subunit RPB2, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa, polymerase (RNA) II subunit B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP30876
  • Protein Name
    DNA-directed RNA polymerase II subunit RPB2
  • Scientific Description
    This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cobo I, Tanaka TN, Chandra Mangalhara K, et al. DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages. Immunity. 2022,55(8):1386-1401.e10. doi: 10.1016/j.immuni.2022.06.022
    Read this paper
  • Hoeksema MA, Shen Z, Holtman IR, et al. Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4. Sci Adv. 2021,7(25). doi: 10.1126/sciadv.abf9808
    Read this paper
  • Jönsson ME, Ludvik Brattås P, Gustafsson C, et al. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nat Commun. 2019,10(1):3182. doi: 10.1038/s41467-019-11150-8
    Read this paper
  • Heinz S, Texari L, Hayes MGB, et al. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018,174(6):1522-1536.e22. doi: 10.1016/j.cell.2018.07.047
    Read this paper