RPB2 antibody [N1], N-term
GTX102535
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPOLR2B
Overview
- SupplierGeneTex
- Product NameRPB2 antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.32 mg/ml
- ConjugateUnconjugated
- Gene ID5431
- Target namePOLR2B
- Target descriptionRNA polymerase II subunit B
- Target synonymsPOL2RB, RPB2, hRPB140, DNA-directed RNA polymerase II subunit RPB2, 3'-5' exoribonuclease, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II second largest subunit, RNA polymerase II subunit 2, RNA polymerase II subunit B2, RNA-directed RNA polymerase II subunit RPB2, polymerase (RNA) II (DNA directed) polypeptide B, 140kDa, polymerase (RNA) II subunit B
- HostRabbit
- IsotypeIgG
- Protein IDP30876
- Protein NameDNA-directed RNA polymerase II subunit RPB2
- Scientific DescriptionThis gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cobo I, Tanaka TN, Chandra Mangalhara K, et al. DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages. Immunity. 2022,55(8):1386-1401.e10. doi: 10.1016/j.immuni.2022.06.022Read this paper
- Hoeksema MA, Shen Z, Holtman IR, et al. Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4. Sci Adv. 2021,7(25). doi: 10.1126/sciadv.abf9808Read this paper
- Jönsson ME, Ludvik Brattås P, Gustafsson C, et al. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors. Nat Commun. 2019,10(1):3182. doi: 10.1038/s41467-019-11150-8Read this paper
- Heinz S, Texari L, Hayes MGB, et al. Transcription Elongation Can Affect Genome 3D Structure. Cell. 2018,174(6):1522-1536.e22. doi: 10.1016/j.cell.2018.07.047Read this paper




