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RPL17 antibody [N1C3-2]

GTX111934
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetRPL17
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPL17 antibody [N1C3-2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.95 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6139
  • Target name
    RPL17
  • Target description
    ribosomal protein L17
  • Target synonyms
    DBA22, L17, PD-1, RPL23, uL22, large ribosomal subunit protein uL22, 60S ribosomal protein L17, 60S ribosomal protein L23, gene encoding putative NFkB activating protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. Two alternative splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Dionne KL, Bergeron D, Landry-Voyer AM, et al. The 40S ribosomal protein uS5 (RPS2) assembles into an extraribosomal complex with human ZNF277 that competes with the PRMT3-uS5 interaction. J Biol Chem. 2019,294(6):1944-1955. doi: 10.1074/jbc.RA118.004928
    Read this paper
  • Landry-Voyer AM, Bilodeau S, Bergeron D, et al. Human PDCD2L Is an Export Substrate of CRM1 That Associates with 40S Ribosomal Subunit Precursors. Mol Cell Biol. 2016,36(24):3019-3032.
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  • Fregoso OI, Das S, Akerman M, et al. Splicing-factor oncoprotein SRSF1 stabilizes p53 via RPL5 and induces cellular senescence. Mol Cell. 2013,50(1):56-66. doi: 10.1016/j.molcel.2013.02.001
    Read this paper