ProductsBack/RRM2 antibody [N1C1]

RRM2 antibody [N1C1]

Name: RRM2 antibody [N1C1]
SKU: GTX103193_G10
Availability: BackOrder

GTX103193

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetRRM2

Overview

Supplier
GeneTex
Product Name
RRM2 antibody [N1C1]
Delivery Days Customer
9
Application Supplier Note
ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.28 mg/ml
Conjugate
Unconjugated
Gene ID6241
Target name
RRM2
Target description
ribonucleotide reductase regulatory subunit M2
Target synonyms
C2orf48; R2; ribonucleoside-diphosphate reductase subunit M2; ribonucleotide reductase M2 polypeptide; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; RR2; RR2M; uncharacterized protein C2orf48
Host
Rabbit
Isotype
IgG
Protein IDP31350
Protein Name
Ribonucleoside-diphosphate reductase subunit M2
Scientific Description
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor.
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The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma. Baroni M et al., 2021 Dec 25, Cells
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RRM1 and ERCC1 as biomarkers in patients with locally advanced and metastatic malignant pleural mesothelioma treated with continuous infusion of low-dose gemcitabine plus cisplatin. Munoz-Montano W et al., 2021 Aug 5, BMC Cancer
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Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line. Kollareddy M et al., 2021 Apr 2, Cells
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Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes. Baroni M et al., 2021 Mar 24, Cancers (Basel)
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anti-EGFR capture mitigates EMT- and chemoresistance-associated heterogeneity in a resistance-profiling CTC platform. Thege FI et al., 2019 Jul 15, Anal Biochem
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The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients. Su YF et al., 2014, PLoS One
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