![ELISA analysis of antigen using GTX60639 RUNX3 antibody [2B3]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng ELISA analysis of antigen using GTX60639 RUNX3 antibody [2B3]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60639/GTX60639_20170912_ELISA_w_23061123_118.webp)
ELISA analysis of antigen using GTX60639 RUNX3 antibody [2B3]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng
RUNX3 antibody [2B3]
GTX60639
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetRUNX3
Overview
- SupplierGeneTex
- Product NameRUNX3 antibody [2B3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ICC/IF: 1/200 - 1/1000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2B3
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID864
- Target nameRUNX3
- Target descriptionRUNX family transcription factor 3
- Target synonymsAML2, CBFA3, PEBP2aC, runt-related transcription factor 3, CBF-alpha-3, PEA2 alpha C, PEBP2 alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, acute myeloid leukemia 2 protein, acute myeloid leukemia gene 2, core-binding factor subunit alpha-3, core-binding factor, runt domain, alpha subunit 3, oncogene AML-2, polyomavirus enhancer-binding protein 2 alpha C subunit, runt related transcription factor 3, transcription factor AML2
- HostMouse
- IsotypeIgG2b
- Protein IDQ13761
- Protein NameRunt-related transcription factor 3
- Scientific DescriptionThis gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5-PYGPYGGT-3 found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Deng R, Huang JH, Wang Y, et al. Disruption of super-enhancer-driven tumor suppressor gene RCAN1.4 expression promotes the malignancy of breast carcinoma. Mol Cancer. 2020,19(1):122. doi: 10.1186/s12943-020-01236-zRead this paper
![FACS analysis of NIH3T3 cells using GTX60639 RUNX3 antibody [2B3]. Green : RUNX3 Red : negative control FACS analysis of NIH3T3 cells using GTX60639 RUNX3 antibody [2B3]. Green : RUNX3 Red : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX60639/GTX60639_20170912_FACS_w_23061123_194.webp)
![IHC-P analysis of cervical cancer tissue using GTX60639 RUNX3 antibody [2B3]. IHC-P analysis of cervical cancer tissue using GTX60639 RUNX3 antibody [2B3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60639/GTX60639_20170912_IHC-P_w_23061123_894.webp)
![WB analysis of HEK293 (1) and RUNX3 (AA: 186-252)-hIgGFc transfected HEK293 (2) cell lysate using GTX60639 RUNX3 antibody [2B3]. WB analysis of HEK293 (1) and RUNX3 (AA: 186-252)-hIgGFc transfected HEK293 (2) cell lysate using GTX60639 RUNX3 antibody [2B3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60639/GTX60639_20170912_WB_w_23061123_585.webp)





