Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA020643ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA020643ESR1HU at dilution of 1:100
S100B Antibody
CSB-PA020643ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetS100B
Overview
- SupplierCusabio
- Product NameS100B Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6285
- Target nameS100B
- Target descriptionS100 calcium binding protein B
- Target synonymsNEF; protein S100-B; S100; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S-100 protein subunit beta; S100-B; S100beta
- HostRabbit
- IsotypeIgG
- Protein IDP04271
- Protein NameProtein S100-B
- Scientific DescriptionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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References
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References
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