Sclerostin antibody [9N13]

GeneTex

Sclerostin antibody [9N13]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

9N13

500 ug/ml

Unconjugated

SOST

sclerostin

CDD; DAND6; sclerostin; SOST1; VBCH

Mouse

IgG2

Sclerostin

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203