SEMA3C antibody [29U11]

GeneTex

SEMA3C antibody [29U11]

9

WB: 1:500 - 1:1000. IHC: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

29U11

200 ug/ml

Unconjugated

SEMA3C

semaphorin 3C

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; sema E; SEMAE; semaphorin E; semaphorin-3C; SemE

Rat

IgG2

Semaphorin-3C

This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203