Western blot analysis of extracts of various cell lines using SEMA3C Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using SEMA3C Polyclonal Antibody at dilution of 1:1000.
SEMA3C Polyclonal Antibody
E-AB-65295
Product group Antibodies
Overview
- SupplierElabscience
- Product NameSEMA3C Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
- UNSPSC12352203