
WB analysis of mouse (A, C) and rat (B, D) brain (A, B) and liver (C, D) lysates using GTX22237 SIAH1 antibody. Dilution : 1microg/ml Loading : 35microg protein in RIPA buffer
SIAH1 antibody
GTX22237
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
ReactivityDrosophila, Human, Mouse, Rat
TargetSIAH1
Overview
- SupplierGeneTex
- Product NameSIAH1 antibody
- Delivery Days Customer9
- Antibody SpecificityThis product is expected to recognize both reported isoforms (NP_003022.3; NP_001006611.1)
- Application Supplier NoteWB: 1-3microg/ml. IP: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID6477
- Target nameSIAH1
- Target descriptionsiah E3 ubiquitin protein ligase 1
- Target synonymsBURHAS; E3 ubiquitin-protein ligase SIAH1; RING-type E3 ubiquitin transferase SIAH1; seven in absentia homolog 1; SIAH1A; siah-1a
- HostGoat
- IsotypeIgG
- Protein IDQ8IUQ4
- Protein NameE3 ubiquitin-protein ligase SIAH1
- Scientific DescriptionThis gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinsons disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
- ReactivityDrosophila, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203