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SIAH1 antibody [N1], N-term

Name: SIAH1 antibody [N1], N-term
SKU: GTX104715_G10
Availability: BackOrder

GTX104715

ApplicationsImmunoFluorescence, ImmunoCytoChemistry

Product group Antibodies

ReactivityMouse

TargetSIAH1

Overview

Supplier
GeneTex
Product Name
SIAH1 antibody [N1], N-term
Delivery Days Customer
9
Applications
ImmunoFluorescence, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID6477
Target name
SIAH1
Target description
siah E3 ubiquitin protein ligase 1
Target synonyms
BURHAS; E3 ubiquitin-protein ligase SIAH1; RING-type E3 ubiquitin transferase SIAH1; seven in absentia homolog 1; SIAH1A; siah-1a
Host
Rabbit
Isotype
IgG
Protein IDQ8IUQ4
Protein Name
E3 ubiquitin-protein ligase SIAH1
Scientific Description
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinsons disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq]
Reactivity
Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Kahle JJ et al., 2011 Feb 1, Hum Mol Genet
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