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ProductsBack/SIAH1 antibody [N1], N-term

SIAH1 antibody [N1], N-term

GTX104715
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
TargetSIAH1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SIAH1 antibody [N1], N-term
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6477
  • Target name
    SIAH1
  • Target description
    siah E3 ubiquitin protein ligase 1
  • Target synonyms
    BURHAS; E3 ubiquitin-protein ligase SIAH1; RING-type E3 ubiquitin transferase SIAH1; seven in absentia homolog 1; SIAH1A; siah-1a
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8IUQ4
  • Protein Name
    E3 ubiquitin-protein ligase SIAH1
  • Scientific Description
    This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinsons disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. Kahle JJ et al., 2011 Feb 1, Hum Mol Genet
    Read more

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